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- Multiple Myeloma Insights
Multiple Myeloma Insights
Long-Term Daratumumab Regimen Benefits Transplant-Ineligible Myeloma Patients
Top StoriesLong-Term Daratumumab Regimen Benefits Transplant-Ineligible Myeloma Patients A 7-year study shows adding daratumumab to standard therapy improves outcomes for newly diagnosed patients ineligible for transplants, supporting its use as an initial treatment option. Read More →EC Approves Regeneron's Lynozyfic for Advanced Multiple Myeloma The EU authorized linvoseltamab for adults whose myeloma returned after multiple treatments, based on evidence of lasting tumor reduction in late-stage trials. Read More → | ||||||||||||||||
Latest ResearchA recent study by Bamfield-Cummings and A (2025) explores how tiny molecules called microRNAs (miRNAs) in blood could help predict treatment resistance and improve care for multiple myeloma. The research focuses on bortezomib, a common chemotherapy drug, and investigates why some patients stop responding to it. By analyzing circulating miRNAs—which act like molecular messengers—the study identifies potential biomarkers that might help doctors detect drug resistance earlier and adjust treatments accordingly. | ||||||||||||||||
Clinical Trials This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks: A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
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Community News
Myeloma, or multiple myeloma, is a blood cancer arising from plasma cells.
It is with great sadness that we share the passing of one of the IMF’s Board Members and longtime philanthropist John O’Dwyer, who lived with myeloma for 18 years until he peacefully passed this Sunday, April 27, surrounded by family and friends.
In ONE week join us to learn about how CAR T-cell therapy works, how it's given to patients, and key side effects to be aware of. | ||||||||||||||||
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