Multiple Myeloma Insights

MRD's Role in Multiple Myeloma Treatment Decisions

April 09, 2025

Latest Research

Recent research highlights the challenges of drug resistance in multiple myeloma, particularly to immunomodulatory drugs (IMiDs). Understanding genetic changes, such as those affecting cereblon, is crucial for developing more effective treatments. A novel cereblon variant has been identified in both newly diagnosed and relapsed cases, which could play a role in resistance (Zhu et al., 2025).

Therapies targeting B-cell maturation antigen (BCMA), such as antibody-drug conjugates and CAR-T cell therapies, show promise in improving patient outcomes. Additionally, advancements in diagnostic tools aim to enhance accuracy and precision in diagnosis, providing more personalized treatment strategies. These developments are crucial for improving patient outcomes in multiple myeloma.

Community News

Myeloma UKApr 01, 2025

Our supporter, Hugh Henderson, recently underwent a head and eyebrow shave in memory of his wife, Anne, who passed away in 2024.

Anne volunteered for Myeloma UK for over fifteen years before she sadly passed away, baking and serving tea and coffee at the Perth Myeloma Support Group Meetings, even before she was diagnosed with myeloma herself. Hugh continues to attend this support group, which has encouraged him to do some fundraising.

We spoke to Hugh about his head shave and he said:

"I always thought to be a fundraiser you had to be able to run marathons, cycle and swim for miles. As a gentleman who is 91 years young, I wasn’t up for those types of fundraisers! After a visit from Myeloma UK fundraising team to the Support Group I realised perhaps there was something else I could do – a headshave.

I spoke to my hairdresser, Vicky, and she was happy to be involved and do the shaving for me. Vicky has been my hairdresser for the last 20 years and in that time she has been desperate to get her hands on my eyebrows! When I spoke to her about shaving my head, she said “and the eyebrows???” So, I had those trimmed off too.

The church that I am a member of suggested hosting a Coffee Morning at the church and having the headshave happen there on 1st February 2025 raising over £4k for Myeloma UK. We also had baskets on the tables for donations for the haematology department at the PRI and raised over £1400 for them too."

Hugh would also like to thank everyone involved in helping to make his fundraiser such a success. 🧡

We would love to hear about your fundraising ideas or plans – get in touch at [email protected] 📩

International Myeloma FoundationApr 02, 2025

Is there a link between multiple myeloma and vitamin D deficiency? The short answer: Yes. IMF CMO Dr. Joseph Mikhael answers this question in the clip. #AsktheIMF#MyelomaMilestone"

Multiple Myeloma Research FoundationApr 01, 2025

💜 You Can Be a Hero Today! 💜

Turn your passion into purpose and help the MMRF accelerate a cure for #myeloma patients everywhere! Starting your own fundraiser is simple and meaningful—your way, your impact. Whether it’s a bake sale, a 5K in a tutu, golfing, or a karaoke showdown, the possibilities are endless.

✨ Step 1: Pick a fun way to raise funds

✨ Step 2: Set up your page (it’s easy!)

✨ Step 3: Rally your friends & change lives!

Visit https://ow.ly/bkEM50VrVuc to get started today!