Multiple Myeloma Insights

This week's must-know community updates, latest research & events

April 02, 2025

Your Essential Guide is Here!

Navigating clinical trials in multiple myeloma

Clinical trials are transforming the treatment landscape for multiple myeloma, bringing innovative therapies closer to those who need them the most.

AllMyHealth’s latest guide, "Navigating Clinical Trials in Multiple Myeloma," simplifies the journey—providing a clear overview of the disease, explaining why clinical trials matter, and detailing the various phases of trials. Learn about common endpoints measured, important regulatory and ethical considerations, the current standard of care, and exciting future perspectives.

Available in both text and audio formats - dive in today and share with your community!

View the Full Report

The report is available for free online on the AllMyHealth website.

www.allmyhealth.io/reports

Latest Research

Researchers have developed a three-dimensional model of multiple myeloma to study interactions between tumor cells and their environment. This model helps assess how immune cells, particularly those engineered with CAR technology, can target and kill myeloma cells.

The focus is on enhancing treatment effectiveness for relapsed or refractory multiple myeloma by understanding cell interactions and responses to therapies. Such models are crucial for improving treatment outcomes by mimicking the complex environment in which myeloma cells grow, allowing for more accurate testing of new therapies, as noted by Luanpitpong et al. (2025).

Clinical Trials

This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

A Study of Daratumumab

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

View the full list of clinical trials →

Community News

Multiple Myeloma Research FoundationMar 27, 2025

Since the MMRF was founded in 1998, we’ve made incredible progress. Multiple myeloma patients are living longer, with survival rates improving from only 3 years to over 10 years.

While we’re proud of these milestones, #myeloma is still an incurable disease, and our work is far from finished. We need your help to continue leading breakthroughs – give today: https://ow.ly/EalR50VpNqU

#MyelomaAwarenessMonth

Myeloma UKMar 29, 2025

Our supporter, Vanessa Ferrett, was diagnosed with myeloma in June last year and has since collaborated with friends, family and her local community to raise over £20,000 and counting.

We spoke to Vanessa about the various fundraising events and she said:

"Firstly, my son, who is obsessed with his hair, shaved his head - I set up a fundraising page and shared on my socials and he raised £5k.

Then a friend said she'd like to run 100km in September to raise more, so I shared this with a few friends and somehow managed to attract 52 runners to do the same. Between them, they ran, walked, and paddled over 6000km. As I didn't have the energy to do the same, I did 30 yoga classes instead. It was great and gave me such a boost at a difficult time.

Last week, another friend asked me to give her a buzz cut at our restaurant and she has raised nearly £5,000 on her page.

We had and still have a WhatsApp chat that we used to encourage and congratulate each other."

Thank you to Vanessa and her team of family and friends for their continued support! 🧡

If you're feeling inspired to arrange your own fundraising event, we would love to help. Get in touch here: https://brnw.ch/21wRF4T

International Myeloma FoundationMar 29, 2025

Myeloma patients are always facing battles, but we are here for you. Have you experienced side effects? How do you manage them? Share with #MyelomaMilestone to spread awareness! More about managing side effects: https://www.myeloma.org/multiple-myeloma-complications